Clinical trial · Interventional
PECBLOCK for the Treatment of Pain After Breast Surgery
The Pectoral Nerve Block (PECBLOCK) for the Treatment of Pain After Breast Cancer Surgery.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Pain after breast cancer surgery could be severe and about 1/3 of patients will develop chronic pain. The PECBLOCK is the injection of local anesthetics between the two pectoral muscles to block pectoral nerves and intercostal nerves innervating the breast. The aim of this study is to evaluate the efficacy of the PECBLOCK performed under echoguidance in minor and major breast surgery. The prevention of chronic pain following surgery will also be evaluated.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Pain | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PECBLOCK under echoguidance | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- PECBLOCK performed with bupivacaine
- description
- Active drug given through PECBLOCK in these patients.
- interventionNames
- Procedure: PECBLOCK under echoguidance
- type
- PLACEBO_COMPARATOR
- label
- PECBLOCK performed with NaCl 0.9%
- description
- Placebo drug given through PECBLOCK in these patients
- interventionNames
- Procedure: PECBLOCK under echoguidance
Primary outcomes (1)
- measure
- Pain score at rest in the recovery room
- timeFrame
- 30 min after entering the recovery room or just before morphine administration if needed
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * women aged 18-85 yrs old * patients ASA status I-IV Exclusion Criteria: * refusal of the PECBLOCK * allergy to a drug used in the protocol (local anesthetic) * patients with chronic pain before the surgery
References
Publications (1)
- DERIVEDCros J, Senges P, Kaprelian S, Desroches J, Gagnon C, Labrunie A, Marin B, Crepin S, Nathan N, Beaulieu P. Pectoral I Block Does Not Improve Postoperative Analgesia After Breast Cancer Surgery: A Randomized, Double-Blind, Dual-Centered Controlled Trial. Reg Anesth Pain Med. 2018 Aug;43(6):596-604. doi: 10.1097/AAP.0000000000000779. PMID 29672368