Clinical trial · Interventional
The Effect of Parenteral Nutrition Supplement on Esophagectomy Patients
The Effect of Parenteral Nutrition Supplement Versus Enteral Nutrition Alone on Nutrition Status After Esophagectomy: A Prospective Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Malnutrition is common in esophagus cancer patients, especially after surgery therapy. Whether parenteral supplement with enteral nutrtion is benificial for patients after esophagectomy is controversial, when compared with enteral nutrition alone. In this study, the investigators are to examine the effect of enteral nutrition supplemented with parenteral nutrtion on nutrition status after esophagectomy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophagus Cancer | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Enteral Nutrition alone for patients after esophagectomy | Other | — | UNRESOLVED |
| Parenteral supplement with enteral nutrition for patients after esophagectomy | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- PN supplement
- description
- Parenteral supplement with enteral nutrition for patients after esophagectomy
- interventionNames
- Other: Parenteral supplement with enteral nutrition for patients after esophagectomy
- type
- ACTIVE_COMPARATOR
- label
- EN alone
- description
- Enteral nutrition alone for patients after esophagectomy
- interventionNames
- Other: Enteral Nutrition alone for patients after esophagectomy
Primary outcomes (2)
- measure
- postoperative laboratory parameters changes for nutrition assessment compared to preoperation
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Clinical diagnosis of esophagus cancer * Undergo esophagectomy * Nasoenteral tube is placed or surgical jejunostomy is performed Exclusion Criteria: * Contraindication for enteral nutrition or parenteral nutrition * Malnutrition before surgery ( BMI \> 30 or \< 18.5) * Hepatic dysfunction preoperatively * Renal dysfunction preoperatively * Infection before surgery * Usage of corticosteroid before surgery
References
Publications (1)
- DERIVEDWu W, Zhong M, Zhu DM, Song JQ, Huang JF, Wang Q, Tan LJ. Effect of Early Full-Calorie Nutrition Support Following Esophagectomy: A Randomized Controlled Trial. JPEN J Parenter Enteral Nutr. 2017 Sep;41(7):1146-1154. doi: 10.1177/0148607116651509. Epub 2016 May 20. PMID 27208039