An Expanded Access Study of Abiraterone Acetate in Patients With Advanced Prostate Cancer Who Have Completed Clinical Study COU-AA-001

Inclusion Criteria:

* Completed 12 cycles of abiraterone acetate under study COU-AA-001
* Last dose of abiraterone acetate within 14 days prior to treatment in this study
* Demonstrates potential to gain clinical benefit with continued abiraterone acetate treatment
* Serum potassium level \>=3.5 mmol/L
* Eastern Cooperative Oncology Group Performance Status of \<3 (Karnofsky Performance Status \>=30%)
* Agrees to protocol-defined use of effective contraception

Exclusion Criteria:

* Serious or uncontrolled co-existent non-malignant disease, including active and uncontrolled infection
* Uncontrolled hypertension
* Abnormal liver function
* Clinically significant heart disease as evidenced by a myocardial infarction in the past 12 months, severe or unstable angina, or New York Heart Association (NYHA) Class III or IV heart disease (patients with a history of atherosclerotic vascular disease requiring coronary or peripheral artery bypass surgery may be enrolled provided the surgery occurred at least 2 years prior to enrollment and after consultation with a cardiologist to insure that the disease is stable)
* Condition or situation which, in the investigator's opinion, may put the patient at significant risk, may confound the study results, or may interfere significantly with patient's participation in the study