Donor Stem Cell Boost in Treating Patients With Low Blood Cells After Donor Stem Cell Transplant

Inclusion Criteria:

1. No evidence of active disease as measured by staging studies pertinent to the particular diagnosis within 1 month of the CD 34+ boost
2. Full donor chimerism as manifested by a ≥ 90% donor peripheral blood total, MNC, and T cell chimerism result on the last two studies prior to the planned CD 34+ boost, with the second study performed within 1 month of the infusion.
3. HHV-6 and CMV negative by PCR for at least 1 month prior to the CD 34+ boost as measured by at least 2 assays within the month timeframe
4. ANC of \< 1000 10\^6/L or maintenance of an ANC ≥ 1000 10\^6/L only with white cell growth factor support
5. Requirement for red cell transfusion to maintain a hemoglobin of ≥ 9.0 g/dL
6. Requirement for red cell transfusion to avoid symptomatic anemia in patients with hemoglobin values of ≤ 11.0 g/dL
7. Requirement for platelet transfusion to maintain a platelet count of ≥ 20 10\^9/L
8. Requirement for platelet transfusion to avoid bleeding in patients with platelet counts ≤ 50 109/L
9. No signs of active acute GVHD (excluding stages I-II skin GVHD)