Clinical trial · Observational
Study of the Association of Nonalcoholic Fatty Liver Disease With Colorectal Malignant Neoplasm
Study of the Prevalence of Colorectal Cancer in Patients With Nonalcoholic Fatty Liver Disease.
NCT01657773CI-TRIAL-00007738NWCcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this sudy is to investigate the prevalence of colorectal cancer (CRC) in patients with nonalcoholic fatty liver disease (NAFLD) and evaluate whether NAFLD is a risk factor for CRC.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Neoplasms | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Nonalcoholic Fatty Liver Disease | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ultrasound examination and Colonoscopy examination | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- colorectal cancer, without nonalcoholic fatty liver disease
- description
- Patients were performed colonoscopy examination for colorectal cancer and who had been foud colorectal cancer proven by biopsy.Then the colorectal cancer patients who had not been diagnosed with nonalcoholic fatty liver disease was based on blood tests and abdomen ultrasound examination.
- interventionNames
- Other: Ultrasound examination and Colonoscopy examination
- label
- colorectal cancer, with nonalcoholic fatty liver disease
- description
- Patients were performed colonoscopy examination for colorectal cancer and who had been foud colorectal cancer proven by biopsy.Then the colorectal cancer patients who had been diagnosed with nonalcoholic fatty liver disease was based on blood tests and abdomen ultrasound examination ultrasonography.
- interventionNames
- Other: Ultrasound examination and Colonoscopy examination
Primary outcomes (3)
- measure
- Ultrasound examination
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 10 Years
Show eligibility criteria text
Inclusion Criteria: * Patients had colonoscopy and * Patients had conventional inspections(blood routine, liver function test and abdomen B ultrasonography) Exclusion Criteria: * Patients were excluded with history of colorectal cancers or polyps, other extraintestinal malignancies and contraindications to colonoscopy. * Patients were excluded who had viral hepatitis, cirrhosis, liver cancer or other liver disease. * Patients ere excluded who drank more than 20g alcohol per day.
References
Publications (1)
- DERIVEDLin XF, Shi KQ, You J, Liu WY, Luo YW, Wu FL, Chen YP, Wong DK, Yuen MF, Zheng MH. Increased risk of colorectal malignant neoplasm in patients with nonalcoholic fatty liver disease: a large study. Mol Biol Rep. 2014 May;41(5):2989-97. doi: 10.1007/s11033-014-3157-y. Epub 2014 Jan 22. PMID 24449368