Clinical trial · Observational
MRI Parenchymal Enhancement: A New Marker of Breast Cancer Risk
Epidemiology of MRI Parenchymal Enhancement: A New Marker of Breast Cancer Risk
NCT01649661CI-TRIAL-00063472completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to learn about how a woman's health history influences what a normal breast looks like on an MRI. The investigators also want to learn about how the amount of different natural hormones a woman has affects how the breast looks on an MRI. The investigator's hope is that this will help to find women at a high-risk of breast cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Free Women | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| questionnaire | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- premenopausal women
- description
- Only women already scheduled for a breast MRI will be included in the study, no additional MRIs will be scheduled for study purposes.
- interventionNames
- Behavioral: questionnaire
- label
- postmenopausal women
- description
- Only women already scheduled for a breast MRI will be included in the study, no additional MRIs will be scheduled for study purposes.
- interventionNames
- Behavioral: questionnaire
Primary outcomes (1)
- measure
- breast cancer risk factors and background parenchymal enhancement (BPE).
- timeFrame
- 1 year
- description
- A comparison of the distribution of breast cancer risk factors in women with low and high levels of BPE. The relationship between risk factors and categories of BPE (minimal/mild/moderate/marked) will be determined using ordinal logistic regression.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * age 21 years or older * be a cancer-free pre- or postmenopausal woman * have no prior personal history of any cancer (including DCIS, excluding nonmelanoma skin-cancer) * able to speak and read English because the questionnaire is only available in English * able to provide informed consent Exclusion Criteria: * are pregnant at the time of MRI * have a prior personal history of any cancer (including DCIS, excluding nonmelanoma skin cancer)
References
Publications (0)
Data not yet available
No reference posted for this study.