Clinical trial · Interventional
Percutaneous Radiofrequency Thermal Ablation in Compressive Thyroid Nodules
Thyroid Nodules Treated With Percutaneous Radiofrequency Thermal Ablation: a Comparative Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Percutaneous radiofrequency thermal ablation (RTA) was reported as an effective tool for the management of thyroid nodules (TNs). This study aims to validate RTA as a valid approach for patients with compressive TNs for whom surgery is contraindicated or refused. Two groups of subjects with TNs (one group to treat with RTA and a matched untreated control group) will be evaluated in term of TN volume, thyroid hormones and clinical symptoms.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Nodule | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Percutaneous Radiofrequency Thermal Ablation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Group A: RTA
- description
- Percutaneous Radiofrequency Thermal Ablation (RTA).
- interventionNames
- Procedure: Percutaneous Radiofrequency Thermal Ablation
- type
- NO_INTERVENTION
- label
- Group B: untreated
- description
- No treatment, only follow-up
Primary outcomes (1)
- measure
- Change from baseline in TN volume
- timeFrame
- 12 months
- description
- Evaluation of TN volume by using Ultrasonography.
Secondary outcomes (6)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 87 Years
Show eligibility criteria text
Inclusion Criteria: * age \> 18 years; * benign thyroid nodules (TYR 2) * solid or predominantly solid (colloid component \< 30%) large (\> 4.0 mL) thyroid nodules * refusal and/or inefficacy of surgery and/or radioiodine therapy. Exclusion Criteria: * pregnancy * malignant or suspicious thyroid nodules.
References
Publications (0)
Data not yet available