Clinical trial · Interventional
Young and Strong: An Education and Supportive Care Intervention Study for Young Women With Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to address gaps in care of young women with breast cancer by determining whether educational interventions focusing on issues unique to young women with breast cancer and healthy lifestyles for women with breast cancer help to improve care of young breast cancer patients. The investigators believe that if addressed early in a young woman's care, concerns related to fertility, body image, sexual dysfunction, and physical activity will improve the satisfaction with care and quality of life of this vulnerable population. The research will be conducted by exporting refined, previously piloted educational interventions to 14 academic sites and 40 community medical clinics. The investigators will compare how interaction with each intervention affects patients' quality of life and satisfaction with quality of care.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Physical Activity Intervention (PAI) | Behavioral | — | UNRESOLVED |
| Young Women's Intervention (YWI) | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Young Women's Intervention (YWI)
- description
- This arm involves administration of an educational intervention that focuses on issues unique to young women with breast cancer, including career development, starting/raising a family, body image, and genetic predispositions to breast cancer.
- interventionNames
- Behavioral: Young Women's Intervention (YWI)
- type
- ACTIVE_COMPARATOR
- label
- Physical Activity Intervention (PAI)
- description
- This arm involves administration of an educational intervention that focuses on developing and/or maintaining a healthy lifestyle for young women with breast cancer, including the benefits of exercise and resources to enhance physical activity after diagnosis.
- interventionNames
- Behavioral: Physical Activity Intervention (PAI)
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * Female age 18-45 years at diagnosis * Within 3 months of stage I-III invasive breast cancer diagnosis * No known recurrence of breast cancer or metastatic breast cancer * Able to read and write in English * Has first appointment with medical oncologist after the provider's practice is enrolled in the study
References
Publications (6)
- BACKGROUNDGreaney ML, Sprunck-Harrild K, Ruddy KJ, Ligibel J, Barry WT, Baker E, Meyer M, Emmons KM, Partridge AH. Study protocol for Young & Strong: a cluster randomized design to increase attention to unique issues faced by young women with newly diagnosed breast cancer. BMC Public Health. 2015 Jan 31;15:37. doi: 10.1186/s12889-015-1346-9. PMID 25636332
- BACKGROUNDPartridge AH, Ruddy KJ, Barry WT, Greaney ML, Ligibel JA, Sprunck-Harrild KM, Rosenberg SM, Baker EL, Hoverman JR, Emmons KM. A randomized study to improve care for young women with breast cancer at community and academic medical oncology practices in the United States: The Young and Strong study. Cancer. 2019 Jun 1;125(11):1799-1806. doi: 10.1002/cncr.31984. Epub 2019 Feb 1. PMID 30707756
- DERIVEDTesch ME, Sorouri K, Zheng Y, Rosenberg SM, Ruddy KJ, Emmons KM, Dutton MC, Partridge AH. Contraception use and changes in young women with newly diagnosed breast cancer. Fertil Steril. 2025 Mar;123(3):488-498. doi: 10.1016/j.fertnstert.2024.09.024. Epub 2024 Sep 19. PMID 39306190
- DERIVEDde Kermadec E, Zheng Y, Rosenberg S, Ruddy KJ, Ligibel JA, Emmons KM, Partridge AH. Fertility concerns and treatment decision-making among national sample of young women with breast cancer. Cancer Med. 2024 Jan;13(1):e6838. doi: 10.1002/cam4.6838. Epub 2023 Dec 22. PMID 38131887
- DERIVEDCarroll BR, Zheng Y, Ruddy KJ, Emmons KM, Partridge AH, Rosenberg SM. Satisfaction with Care and Attention to Age-Specific Concerns by Race and Ethnicity in a National Sample of Young Women with Breast Cancer. J Adolesc Young Adult Oncol. 2024 Feb;13(1):105-111. doi: 10.1089/jayao.2023.0068. Epub 2023 Aug 18. PMID 37594766
- DERIVEDCook EE, Rosenberg SM, Ruddy KJ, Barry WT, Greaney M, Ligibel J, Sprunck-Harrild K, Holmes MD, Tamimi RM, Emmons KM, Partridge AH. Prospective evaluation of the impact of stress, anxiety, and depression on household income among young women with early breast cancer from the Young and Strong trial. BMC Public Health. 2020 Oct 6;20(1):1514. doi: 10.1186/s12889-020-09562-z.