Clinical trial · Interventional
Physical Activity in Pediatric Cancer (PAPEC)
Physical Activity in Pediatric Cancer Patients With Solid Tumor Trial
NCT01645436CI-TRIAL-00022443PAPECcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this randomized controlled trial on Physical Activity and Pediatric Cancer (PAPEC) is to assess the impact of an exercise program intervention in pediatric cancer patients undergoing chemotherapy for solid tumors. The investigators hypothesized the intervention will have a beneficial effect on the study outcomes.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pediatric Cancer | Childhood Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| exercise training | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- treatment (exercise)
- description
- combined inpatient physical training (aerobic + strength) over neoadjuvant chemotherapy. The intervention will include three weekly exercise sessions of 60-90 minutes, and will be held in child's room or in a pediatric gym specifically enabled on the aforementioned hospital, depending on the children's health status.
- interventionNames
- Other: exercise training
- type
- NO_INTERVENTION
- label
- control (usual care)
- description
- Usual hospital care with no exercise
Primary outcomes (1)
- measure
- Muscle strength (kg) measured in 5-repetition maximum (5RM) leg and bench press and lateral row exercise tests
- timeFrame
- up to 3 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 4 Years
- Maximum age
- 16 Years
Show eligibility criteria text
Inclusion Criteria: * age range between 4 to 16 years old, undergoing treatment for primary tumors (excluding central nervous system tumors) treated in the Hospital Infantul Niño jesús and residents in Madrid community. - Exclusion Criteria: * age\<4 years or \>16 years, other tumours
References
Publications (1)
- DERIVEDSoares-Miranda L, Fiuza-Luces C, Lassaletta A, Santana-Sosa E, Padilla JR, Fernandez-Casanova L, Lorenzo-Gonzalez R, Lopez-Mojares LM, Perez M, Perez-Martinez A, Lucia A. Physical Activity in Pediatric Cancer patients with solid tumors (PAPEC): trial rationale and design. Contemp Clin Trials. 2013 Sep;36(1):106-15. doi: 10.1016/j.cct.2013.05.012. Epub 2013 Jun 5. PMID 23747802