Clinical trial · Interventional
Endoscopic Ultrasound (EUS)-Guided Ablation of Pancreatic Cysts
NCT01643460CI-TRIAL-00057800completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to track outcomes and complications of patients at IUMC referred by physicians for EUS-guided pancreatic cyst ablation. This information is essential in order to disseminate future published information to physicians about this technique. A database will be created to track these patients undergoing an already scheduled/planned procedure. Phone calls at selected intervals will be made following the procedure to track any complications that occur
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cystadenoma, Mucinous | Mucinous Cystadenoma | ONTOLOGY_EXACT | 0.98 |
| Pancreatic Cyst | — | UNRESOLVED | — |
| Pancreatic Intraductal Papillary-Mucinous Neoplasm | Pancreatic Intraductal Papillary Mucinous Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Papillary Mucinous Cystadenoma, Borderline Malignancy | Borderline Papillary Mucinous Cystadenoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 98% Ethanol & Paclitaxel injection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- 98% Ethanol with Paclitaxel injection
- interventionNames
- Procedure: 98% Ethanol & Paclitaxel injection
Primary outcomes (1)
- measure
- Cyst resolution
- timeFrame
- 6 months
- description
- 1\. Patients will undergo EUS-guided cyst ablation with ethanol +/- paclitaxel as indicated for their scheduled procedure. 2. Patients will return 3 months after initial ablation for a repeat EUS, and ablation will be repeated if cyst size is \>10mm in diameter. 3. CT or MRI imaging will be performed 3 months after the second procedure to assess for cyst resolution.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients referred between January 2009 and February 2016 to EUS at IUMC for pancreatic cyst ablation and with no contraindications for anticipated safe and successful performance of the procedure. 2. Patient at least 18 years of age. Exclusion Criteria: 1. Investigator deems cyst does not meet safety or need for cyst ablation. 2. Subject not competent to sign consent
References
Publications (2)
- DERIVEDKim KH, McGreevy K, La Fortune K, Cramer H, DeWitt J. Sonographic and cyst fluid cytologic changes after EUS-guided pancreatic cyst ablation. Gastrointest Endosc. 2017 Jun;85(6):1233-1242. doi: 10.1016/j.gie.2016.09.011. Epub 2016 Sep 17. PMID 27650271
- DERIVEDDeWitt JM, Al-Haddad M, Sherman S, LeBlanc J, Schmidt CM, Sandrasegaran K, Finkelstein SD. Alterations in cyst fluid genetics following endoscopic ultrasound-guided pancreatic cyst ablation with ethanol and paclitaxel. Endoscopy. 2014 Jun;46(6):457-64. doi: 10.1055/s-0034-1365496. Epub 2014 Apr 25. PMID 24770971