Clinical trial · Interventional
A Comparison of Single Versus Double Evacuation for Treatment of Hydatidiform Mole
A Comparison of Single Versus Double Evacuation for Treatment of Hydatidiform
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Hydatidiform mole is a common complication of pregnancy with an incidence of 1in 400 pregnancies in India. Although this is a benign condition , it is having the malignant potential too. A repeat curettage after evacuation of hydatidiform mole was generally advocated till 1990s. A thorough curettage at the time of initial evacuation was not performed because of larger size of uterus and risk of perforation. Subsequently a number of studies assessed the usefulness of repeat curettage and found it was unnecessary and not cost effective . However all these studies are retrospective in design and conducted in developed countries where hydatidiform mole is diagnosed earlier because of wider use of ultrasonography. Thus there is a need to perform a well designed prospective study to compare the effectiveness of single evacuation with double evacuation in treatment of hydatidiform mole for prevention of Gestational Trophoblastic Neoplasia.This study compares the effectiveness of single evacuation versus double evacuation for treatment of hydatidiform mole for prevention of gestational trophoblastic neoplasia .
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hydatidiform Mole | Molar Pregnancy | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Suction and evacuation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Single evacuation of mole,
- interventionNames
- Procedure: Suction and evacuation
- type
- ACTIVE_COMPARATOR
- label
- Double evacuation of mole
- interventionNames
- Procedure: Suction and evacuation
Primary outcomes (1)
- measure
- Proportion of patents diagnosed as GTN following treatment in each group
- timeFrame
- Six months following evacuation
Secondary outcomes (3)
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 15 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * Ultrasound confirmed complete mole Exclusion Criteria: * Partial mole * History of treatment for molar pregnancy like prior evacuation or chemotherapy * Women requiring hysterectomy for treatment of H Mole
References
Publications (0)
Data not yet available