Clinical trial · Interventional
Effect of Salpingectomy During Conservative Hysterectomy
Effect of Total Salpingectomy During Conservative Hysterectomy for Benign Disease on Ovarian Function: Non Inferiority Randomized Controlled Trial
NCT01628432CI-TRIAL-00035395SALPINGOVAcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study compares the effect of bilateral salpingectomy associated with conservative hysterectomy on ovarian function to the standard hysterectomy with conservation of both ovaries and tubes in terms of hormone assays, ovarian ultrasound evaluation, complications, quality of life.
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adenomyosis, Endometriosis | — | UNRESOLVED | — |
| Cervical Dysplasia | Cervical Intraepithelial Neoplasia | ALIAS | 0.90 |
| Dysfunctional Uterine Bleeding | — | UNRESOLVED | — |
| Genital Diseases, Female | — | UNRESOLVED | — |
| Hysterotomy; Affecting Fetus | — | UNRESOLVED | — |
| Leiomyomata Uteri | — | UNRESOLVED | — |
| Uterine Prolapse | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| conservative hysterectomy I | Procedure | — | UNRESOLVED |
| Conservative hysterectomy II | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- conservative hysterectomy I
- description
- bilateral salpingectomy during hysterectomy with conservation of the ovaries
- interventionNames
- Procedure: conservative hysterectomy I
- type
- ACTIVE_COMPARATOR
- label
- conservative hysterectomy II
- description
- standard conservative hysterectomy with conservation of both ovaries and tubes
- interventionNames
- Procedure: Conservative hysterectomy II
Primary outcomes (1)
- measure
- percentage of patients with more than 20% diminution of AMH logarithm at one year (12 months)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 52 Years
Show eligibility criteria text
Inclusion Criteria: * age ≥ 18 years and less than 52 years * indication of a conservative hysterectomy for benign disease * signed informed consent * non menopausal women (AMH \>0,21 ng/ml) Exclusion Criteria: * pregnancy * desire of future pregnancy * menopausal status * patient unable to give informed consent * any physical or psychiatric condition that could impair with patient's ability to cooperate with post operative data collection * previous salpingo and /or oophorectomy (unilateral or bilateral) * genital cancer disease or atypical endometrial hyperplasia * hyperandrogenia * any ovarian mass that needs surgical exploration * any immunotherapy that could interfere with immunological tests
References
Publications (0)
Data not yet available
No reference posted for this study.