Clinical trial · Interventional
Confocal Micro-endoscopy in Head and Neck Cancer/Micro Endoscopie Confocale (MEC)Oto-Rhino-Laryngologie (ORL)
Clinical Evaluation of Confocal Microscopy in Head and Neck Cancer
NCT01626638CI-TRIAL-00050159MEC ORLcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The primary objective is to validate the diagnostic correlation between the intraoperative microendoscopic images and the conventional histological analysis on biopsy and/or surgical specimens on patients with epidermoid carcinoma.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Malignant Pharyngo Laryngeal Tumors | — | UNRESOLVED | — |
| Pre-malignant Pharyngo Laryngeal Tumors | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Confocal Micro Endoscopy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Experimental
- interventionNames
- Procedure: Confocal Micro Endoscopy
Primary outcomes (1)
- measure
- Diagnostic correlation between confocal micro endoscopy and conventional histology
- timeFrame
- at an average of 18 months
Secondary outcomes (1)
- measure
- Histological diagnostic with confocal micro endoscopy (MEC) VS conventional histological analysis
- timeFrame
- At the time of the biopsy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with malignant and pre-malignant pharyngo laryngeal tumors in whom direct laryngoscopy was performed under general anesthesia with biopsies for diagnostic or endoscopic removal * \> 18 years * signed ICF Exclusion Criteria: * Persons deprived of liberty * Patients with history of allergy to patent blue * Pregnant women or breastfeeding women
References
Publications (1)
- DERIVEDVillard A, Breuskin I, Casiraghi O, Asmandar S, Laplace-Builhe C, Abbaci M, Moya Plana A. Confocal laser endomicroscopy and confocal microscopy for head and neck cancer imaging: Recent updates and future perspectives. Oral Oncol. 2022 Apr;127:105826. doi: 10.1016/j.oraloncology.2022.105826. Epub 2022 Mar 19. PMID 35316771