Clinical trial · Interventional
I-Scan Versus High-definition White Light
A Randomized Controlled Trial Comparing High-definition White Light Colonoscopy to I-Scan Enhanced Colonoscopy for Adenoma Detection in a Population at Increased Risk of Colorectal Cancer. (A Pilot Study)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study is to assess whether the use of I-scan during colonoscopy leads to an increased yield of adenomas in the colon among a population at increased risk for CRC. Primary Outcome: To estimate the mean number of adenomas per colonoscopy for both high definition white light colonoscopy and I-scan enhanced colonoscopy Secondary Outcomes: 1. To estimate the recruitment rate 2. Number of adenomas detected in the right colon during the second look
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| HD Colon | Device | — | UNRESOLVED |
| I-Scan 1 | Device | — | UNRESOLVED |
| I-Scan 2 | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- I-Scan 1
- description
- I-Scan 1 modality will be used by the endoscopist for the entire procedure
- interventionNames
- Device: I-Scan 1
- type
- EXPERIMENTAL
- label
- HD Colon
- description
- High definition white light modality will be used by the endoscopist for the entire procedure
- interventionNames
- Device: HD Colon
- type
- EXPERIMENTAL
- label
- I-scan 2
- description
- I-Scan 2 modality will be used by th endoscopist through out the procedure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 74 Years
Show eligibility criteria text
Inclusion Criteria: * All increased risk patients (Patients with family history or personal history of Colon Polyps or Colon Cancer and FOBT positive) referred for a screening colonoscopy at the Forzani and MacPhail Colon Cancer Centre will be considered for enrollment Exclusion Criteria: * Average risk patients * Previous Colon surgery * Hereditary Polyposis syndromes * Suspected polyps or CRC before colonoscopy that have been suggested by another modality (Barium enema, Virtual colonoscopy, Flexible Sigmoidoscopy)
References
Publications (0)
Data not yet available