Clinical trial · Interventional
Split Dose Polyethylene Glycol (PEG) + Clear Fluids Versus Split Dose PEG + Low-Residue Diet
A Randomized Prospective Trial Comparing Split Dose Polyethylene Glycol-Based Lavage With Clear Fluids Versus Split Dose Polyethylene Glycol-Based Lavage With a Low-Residue Diet in Preparation of Patients for Colonoscopy.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of the study is to examine the effect of adding a strict low-residue lunch on the day before colonoscopy has on clinical efficacy and patient tolerability of bowel preparation, with patients receiving split-dose Polyethylene Glycol Based Lavage. The primary outcomes will be 1) quality of preparation in cleansing the colon and 2) patient satisfaction
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Split-dose PEG Based Lavage (2L + 2L) with Low-Fibre Lunch Dietary instructions | Other | — | UNRESOLVED |
| Split-dose PEG Based Lavage (2L + 2L) with Standard Dietary Instructions | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Split-dose PEG Based Lavage (2L + 2L) + Low-fiber Diet
- description
- Patients randomized to this arm will have a split-dose Polyethylene Glycol Based lavage (2L + 2L), have a low-fibre diet 4 days prior to Colonoscopy and the day before Colonoscopy, have a low-fibre breakfast, a low-fibre lunch by 2PM and then drink only clear fluids until after the procedure is completed.
- interventionNames
- Other: Split-dose PEG Based Lavage (2L + 2L) with Low-Fibre Lunch Dietary instructions
- type
- PLACEBO_COMPARATOR
- label
- Split-dose PEG Based Lavage (2L + 2L) + Clear fluid diet
- description
- Patients randomized to this arm will have a split-dose Polyethylene Glycol Based lavage (2L + 2L), have a low-fibre diet 4 days prior to Colonoscopy and the day before Colonoscopy, have a low-fibre breakfast and then drink only clear fluids until after the procedure is completed.
- interventionNames
- Other: Split-dose PEG Based Lavage (2L + 2L) with Standard Dietary Instructions
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 74 Years
Show eligibility criteria text
Inclusion Criteria: * Patients between 18 to 74 Years referred to the Forzani \& MacPhail Colon Cancer Screening Centre in Calgary, Alberta, Canada for Colonoscopy will be considered for inclusion. Exclusion Criteria: * Patients with acute Coronary Syndrome, * Congestive Heart Failure, * Unstable Angina, * Known or suspected Renal Failure, * Ascites, * Known or suspected Bowel obstruction or * Other comorbidities that may prevent Colonoscopy will be excluded.
References
Publications (0)
Data not yet available