Clinical trial · Interventional
Impact of Probiotics on the Intestinal Microbiota
Impact of Probiotics on the Intestinal Microbiota and Its Association With Postoperative Outcome After Colorectal Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to assess the impact of probiotic administration (Saccharomyces boulardii) on patients undergoing colorectal resections comparing to the routine protocol by assessing: (1)intestinal microbiota modulation using RT-PCR to measure cytokine in the mucosa; (2) assess postoperative complications, mainly infectious and mortality, as well as length of hospital stay
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Saccharomyces boulardii | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control group
- description
- No intervention at all
- type
- EXPERIMENTAL
- label
- Study group
- description
- Use of Saccharomyces boulardii, 100mg for at least seven days before surgery
- interventionNames
- Dietary Supplement: Saccharomyces boulardii
Primary outcomes (1)
- measure
- Mucosal cytokine
- timeFrame
- April 2013
- description
- To assess mucosal cytokine levels
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * older than 18 years old * intend to undergo elective colon resection at the UFMG Hospital Exclusion Criteria: * Patients in use of steroids * Patients unable to receive the probiotics for, at least, 7 days before the operation * Changes to the operation strategy * Patients that discontinued probiotic use * Patients who had previously taken any probiotic or prebiotic
References
Publications (0)
Data not yet available