Clinical trial · Observational
Treatment Resistance Related With Gene Expression Profile of Diffuse Large B-cell Lymphoma
Retrospective Analysis of Diffuse Large B-cell Lymphoma: Identification of Factors Associated With Treatment Resistance Via Gene Expression Profile
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators perform a retrospective microarray gene expression profiling study of FFPE from a cohort of DLBCL patients with whole genome cDNA mediated Annealing Selection and Ligation (WG-DASL) assay. The investigators also study the pattern of microRNA from patients with diffuse large B-cell lymphoma. The results of gene expression profiles and microRNA is correlated with clinical outcomes of diffuse large B-cell lymphoma.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Diffuse Large B-cell Lymphoma | Diffuse Large B-Cell Lymphoma | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Diffuse large B-cell lymphoma
- description
- Patients diagnosed and treated at the Samsung Medical Center
Primary outcomes (1)
- measure
- Number of patients who relapse or progress after 1st line chemotherapy
- timeFrame
- two years
Secondary outcomes (1)
- measure
- Number and type of genes and microRNA which are significantly related with relapse or progression (P < 0.05)
- timeFrame
- two years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Patients diagnosed with diffuse large B-cell lymphoma * Patients with tissue blocks available for study * Patients with adequate medical records Exclusion Criteria: * Patients diagnosed with other subtypes of lymphoma
References
Publications (0)
Data not yet available