Clinical trial · Interventional
Tumor Markers in Lung Cancer: DCAMLK-1LK-1
Tumor Markers in Lung Cancer: DCAMLK-1LK-1: A Pilot Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
DCAMLK1 is a Ca2+ - ca/modulin (CaM) - dependent protein kinase that is a marker of stem cells in colonic crypts. Mutations within the stem cell population are thought to be responsible for the development of most colorectal carcinomas and studies have shown that DCAMLK1 is highly expressed in these tumors. Since the lung is an embryological development of the foregut, the investigators speculate that DCAMLK1 will also be upregulated in lung cancers. The aim of this pilot study is to measure DCAMLK1 levels in the blood of patients with suspected malignant and benign lung diseases, and to correlate DCAMKL1 levels with smoking status.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Smoking | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| DCAM levels in blood | Other | — | UNRESOLVED |
| Measure DCAM levels in blood | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Lung Cancer
- description
- Diagnostic
- interventionNames
- Other: Measure DCAM levels in blood
- type
- OTHER
- label
- Lung Disease
- description
- Diagnostic
- interventionNames
- Other: DCAM levels in blood
Primary outcomes (1)
- measure
- Tumor Markers in Lung Cancer:
- timeFrame
- 6 months
- description
- DCAMLK-1LK-1 levels will be measured in the blood of patients with Lung Cancer and compared to that of controls with other lung diseases.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * \>45 years of age Exclusion Criteria: * Unable to provide informed consent
References
Publications (0)
Data not yet available