Clinical trial · Interventional
Reflexology: An Intervention for Advanced Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to test a complementary therapy intervention (reflexology) that will assist in improving quality of life (QOL) for women undergoing chemotherapy for late stage (III or IV) breast cancer within the context of conventional medical care. Quality of life will be assessed via intermediate indicators: 1) physical indicators (greater physical functioning, lower presence of symptoms) 2) emotional indicators (greater spirituality, lower anxiety, and lower depressive symptomology); and the outcome indicator of quality of life.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Placebo Sessions | Other | — | UNRESOLVED |
| Reflexology Sessions | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Group A
- description
- Reflexology Sessions: One session per week performed by certified reflexologist for four consecutive weeks.
- interventionNames
- Other: Reflexology Sessions
- type
- PLACEBO_COMPARATOR
- label
- Group B
- description
- Placebo Sessions: One session per week performed by research aide for four consecutive weeks.
- interventionNames
- Other: Placebo Sessions
- type
- NO_INTERVENTION
- label
- Group C
- description
- Control; no foot sessions
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of Stage III or IV breast cancer, or Stage I or II with Metastasis or Recurrence * Able to perform basic ADLs * Free of diagnosis of mental illness on chart * Able to speak and understand English * Access to a telephone * Receiving chemotherapy at intake into the study * Palliative Prognostic Score of 11 or lower * Oriented to time, place, and person as determined by nurse recruiter Exclusion Criteria: * Receiving investigational new drug chemotherapy * Receiving hospice care at intake * Living in nursing home or similar facility * Bedridden * Undergoing bone marrow transplant * Regularly using foot massage * Regularly using reflexology * Regularly using pedicure with foot massage
References
Publications (4)
- BACKGROUNDSikorskii A, Wyatt G, Victorson D, Faulkner G, Rahbar MH. Methodological issues in trials of complementary and alternative medicine interventions. Nurs Res. 2009 Nov-Dec;58(6):444-51. doi: 10.1097/NNR.0b013e3181bf15fe. PMID 19918155
- BACKGROUNDRahbar MH, Wyatt G, Sikorskii A, Victorson D, Ardjomand-Hessabi M. Coordination and management of multisite complementary and alternative medicine (CAM) therapies: experience from a multisite reflexology intervention trial. Contemp Clin Trials. 2011 Sep;32(5):620-9. doi: 10.1016/j.cct.2011.05.015. Epub 2011 Jun 2. PMID 21664296
- BACKGROUNDWyatt G, Sikorskii A, Rahbar MH, Victorson D, Adams L. Intervention fidelity: aspects of complementary and alternative medicine research. Cancer Nurs. 2010 Sep-Oct;33(5):331-42. doi: 10.1097/NCC.0b013e3181d0b4b7. PMID 20467309
- RESULTSikorskii A, Wyatt GK, Siddiqi AE, Tamkus D. Recruitment and early retention of women with advanced breast cancer in a complementary and alternative medicine trial. Evid Based Complement Alternat Med. 2011;2011:734517. doi: 10.1093/ecam/nep051. Epub 2011 Feb 14. PMID 19620179