Clinical trial · Interventional
Safety and Efficacy Study of Ultrasonic Coagulation Device and Bipolar Energy Sealing System
Comparison of Surgical Outcomes Between Papillary Thyroid Cancer Patients Treated With the Harmonic ACE® Scalpel and LigaSure Precise™ Instrument During Conventional Thyroidectomy: A Single-blind Prospective Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of the study is to evaluate differences between use of Ultrasonic Coagulation Device (New Harmonic ACE™, Ethicon endo-surgery) and Bipolar Energy Sealing System (LigaSure Precise™, Covidien) in surgery for thyroid cancer. Abbreviations: Ultrasonic Coagulation Device (UC), Bipolar Energy Sealing System (BES), Recurrence-free survival (RFS), Overall survival (OS)
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Cancer | Malignant Thyroid Gland Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| bipolar energy sealing system (LigaSure Precise) | Device | — | UNRESOLVED |
| Ultrasonic coagulation device (Harmonic ACE® scalpel) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Ultrasonic coagulation device
- description
- Comparison of Surgical Outcomes Between Papillary Thyroid Cancer Patients Treated with the Ultrasonic coagulation device (Harmonic ACE® Scalpel) and the bipolar energy sealing system (LigaSure Precise) during Conventional Thyroidectomy
- interventionNames
- Device: Ultrasonic coagulation device (Harmonic ACE® scalpel)
- type
- OTHER
- label
- Bipolar Energy Sealing System
- description
- Comparison of Surgical Outcomes Between Papillary Thyroid Cancer Patients Treated with the Ultrasonic coagulation device (Harmonic ACE® Scalpel) and the bipolar energy sealing system (LigaSure Precise) during Conventional Thyroidectomy
- interventionNames
- Device: bipolar energy sealing system (LigaSure Precise)
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. an age between 20 and 80 years old who are diagnosed as thyroid cancer or suspicious papillary thyroid cancer in fine needle aspiration biopsy 2. patients who are agree with the study enrollment Exclusion Criteria: 1. an age under 20 or over 80 years 2. severe co-morbidities that were contraindications for thyroid surgery (e.g., severe liver, heart, kidney, or pulmonary problems) 3. a lack of consent to participate in the study 4. the inability to include a patient in clinical trials according to the regulations or laws in Korea 5. the inability to complete regular follow-up visits (e.g., immigration) 6. the use of modified radical neck dissection due to lateral neck node metastasis 7. prior thyroid surgery or cervical irradiation 8. active enrollment in another clinical trial 9. the intention of the patient to undergo an additional operation at the time of the thyroid surgery (e.g., mastectomy and thyroidectomy at the same time) 10. the desire to undergo endoscopic or robot-assisted thyroidectomy
References
Publications (0)
Data not yet available