Clinical trial · Interventional
Comparison Colon Capsule Endoscopy vs Optical Colonoscopy for Colorectal Cancer Screening in Familiar-Risk Population
Effectiveness of Colon Capsule Endoscopy as Colorectal Cancer Method of Screening in The Familiar-Risk Population
NCT01557101CI-TRIAL-00013358CRIBADOcompletedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine if the adherence to screening in first grade relatives of patients with CCR is higher than optical colonoscopy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer, Genetics of | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| COLON CAPSULE ENDOSCOPY ADHERENCE | Procedure | — | UNRESOLVED |
| OPTICAL COLONOSCOPY ADHERENCE | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- COLON CAPSULE ENDOSCOPY
- interventionNames
- Procedure: COLON CAPSULE ENDOSCOPY ADHERENCE
- type
- OTHER
- label
- OPTICAL COLONOSCOPY
- interventionNames
- Procedure: OPTICAL COLONOSCOPY ADHERENCE
Primary outcomes (1)
- measure
- Participation to colorectal cancer screening in first-degree relatives of patients with colorectal cancer
- timeFrame
- 6 month follow up
- description
- Assess whether colon capsule endoscopy increases participation to colorectal cancer screening in first-degree relatives of patients with colorectal cancer
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Asymptomatic first-degree relatives (parents, siblings or children) of CRC patients aged less than 60 years or with two or more first-degree relatives of any age. * Signing of informed consent. Exclusion Criteria: * Personal history of adenoma or CRC. * History of hereditary CRC. * Chronic inflammatory disease. * Presence of digestive symptoms. * Patients with swallowing problems (dysphagia). * Personal history of gastrointestinal surgery. * Enteritis radioactive. * Renal failure. * Congestive heart failure * Allergy or other contraindication to Bysacodyl to PEG or phosphates. * Pregnancy. * Suspected bowel obstruction or intestinal strictures or fistulas known. * Colectomy. * Paralysis with impaired intestinal motility. * Any other process that the investigator's discretion to make inadequate participation.
References
Publications (1)
- DERIVEDAdrian-de-Ganzo Z, Alarcon-Fernandez O, Ramos L, Gimeno-Garcia A, Alonso-Abreu I, Carrillo M, Quintero E. Uptake of Colon Capsule Endoscopy vs Colonoscopy for Screening Relatives of Patients With Colorectal Cancer. Clin Gastroenterol Hepatol. 2015 Dec;13(13):2293-301.e1. doi: 10.1016/j.cgh.2015.06.032. Epub 2015 Jun 29. PMID 26133904