Clinical trial · Interventional
Role of Melatonin Supplementation in Follicular Fluid of in Vitro Fertilization (IVF) Patients With Polycystic Ovarian Syndrome
NCT01540747CI-TRIAL-00006355completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To evaluate the effects of melatonin supplementation on the main in vitro fertilization (IVF) outcomes during ovarian stimulation in patients with Polycystic ovarian syndrome (PCOS).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Polycystic Ovary Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Myo-inositol + folic acid | Dietary Supplement | — | UNRESOLVED |
| Myo-inositol + folic acid + melatonin | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Inofolic plus
- description
- 178 patients
- interventionNames
- Dietary Supplement: Myo-inositol + folic acid + melatonin
- type
- ACTIVE_COMPARATOR
- label
- Inofolic
- description
- 180 patients
- interventionNames
- Dietary Supplement: Myo-inositol + folic acid
Primary outcomes (4)
- measure
- Number of mature oocytes
- measure
- embryo quality
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 27 Years
- Maximum age
- 38 Years
Show eligibility criteria text
Inclusion Criteria: * diagnosis of PCOS * irregular menstrual cycle (\> than 28-30 days) * normal uterine cavity * body mass index of 20 to 26 Kg/m2 * first IVF treatment Exclusion Criteria: * presence of tubal, uterine, genetics and male causes of infertility * diagnosis of cancer * hormonal treatment in the last six months
References
Publications (0)
Data not yet available
No reference posted for this study.