Clinical trial · Interventional
Paullinia Cupana for Anorexia in Oncologic Patients
Guarana (Paullinia Cupana) for Anorexia Related to Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Denutrition, lost of weight and anorexia are present in many oncologic patients at any time of the disease. Anorexia is the spontaneous loss of appetite and many changes in the metabolism are made in this case, leading to this syndrome called anorexia-cachexia, that includes changes in the tumoral response and inflammatory pathways. The guaraná (Paullinia cupana) is originally from Brazil and Venezuela and has been used culturally for headaches, muscle pains, depression and others. As it has shown a good response and tolerability for fatigue, the investigators decide to try guaraná for anorexia. Patients will receive guaraná as capsules of 50 mg twice daily, for 4 weeks, and will be weighted and respond questionaries about quality of life.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anorexia | — | UNRESOLVED | — |
| Cancer-related Problem/Condition | — | UNRESOLVED | — |
| Loss of Weight | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Paullinia cupana | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Paullinea cupana
- description
- 50mg of Paullinia cupana as capsule, twice daily
- interventionNames
- Drug: Paullinia cupana
Primary outcomes (1)
- measure
- weight
- timeFrame
- eight weeks
- description
- Patients will considered to respond to guaraná if the gain 5% or more of his inicial weight during the treatment period
Secondary outcomes (1)
- measure
- quality of life
- timeFrame
- eight weeks
- description
- Weekly patients will answer questionaries about quality of life like FACT-G
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * adults (18 years old and older) * palliative care or oncologic treatment * loss of weight * anorexia Exclusion Criteria: * gastrointestinal obstruction * blood pressure not controlled * diabetes not treated
References
Publications (0)
Data not yet available