Clinical trial · Interventional
Evaluation of Reduced-volume PEG Bowel Preparation Administered the Same Day of Colonoscopy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The conventional total dose of 4 L of polyethylene glycol (PEG) given the day before the procedure is safe and effective. It has been the standard cleansing regimen for the last 25 years. To overcome the difficulty in completing the bowel preparation due to large volume and/or taste, reduced-volume (mixed) bowel preparation of bisacodyl and 2 L of PEG have been shown to provide adequate colon cleansing and better tolerability. LoVol-esse is a reduced-volume PEG-based bowel preparation to be used in combination with bisacodyl and designed to improve patient tolerability and attitude toward bowel cleansing prior to colonoscopy thanks to the reduced volume and improved taste. The present study is intended to compare the new dosing regimen of the bowel lavage solution given the same day compared with standard PEG formulation (SELG 1000) given the day before colonoscopy.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Colon | — | UNRESOLVED | — |
| Colonic Polyps | — | UNRESOLVED | — |
| Inflammatory Bowel Disease | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PEG low volume with bisacodyl | Drug | — | UNRESOLVED |
| polyethylene glycol (PEG) | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- polyethylene glycol (PEG)
- interventionNames
- Drug: polyethylene glycol (PEG)
- type
- EXPERIMENTAL
- label
- PEG low volume with bisacodyl
- interventionNames
- Drug: PEG low volume with bisacodyl
Primary outcomes (1)
- measure
- Evaluation of the overall quality of bowel preparation
- timeFrame
- 4 months
- description
- Quality of preparation will be graded according to the Ottawa Scale.
Secondary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * both sexes * aged between 18 and 85 yr * undergoing a complete colonoscopy Exclusion Criteria: * known or suspected gastrointestinal obstruction or perforation * toxic megacolon * major colonic resection * pregnant or at risk of becoming pregnant women * lactating women * inability to comprehend the full nature and purpose of the study * no signed informed consent prior to inclusion in the study * known or suspected hypersensitivity to the active principles or other ingredients * history of anaphylaxis to drugs or allergic reactions in general
References
Publications (0)
Data not yet available