Clinical trial · Interventional
3D Breast Ultrasound Elastography in Patients Under Neoadjuvant Chemotherapy
Imagerie 3D d'élasticité du Sein Par échographie Ultrarapide au Cours d'un Traitement Par chimiothérapie néoadjuvante.
NCT01531036CI-TRIAL-00094151completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Breast Ultrasound Elastography is a complementary technique permitting a better characterization of breast lesions. 3D breast ultrasound elastography is a novel technique permitting a volumetric calculation of lesion stiffness. This could be particularly useful in patients with large breast tumors under pre-operative chemotherapy
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Malignant Breast Tumours | Malignant Breast Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 3D Ultrasound elastography by means of shear wave propagation into breast tissue | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- shear wave imaging
- description
- Single arm study evaluating breast 3D elastography by means of shear wave propagation into breast tissue.
- interventionNames
- Device: 3D Ultrasound elastography by means of shear wave propagation into breast tissue
Primary outcomes (1)
- measure
- 3D volumetric elasticity measurements
- timeFrame
- 10min
- description
- An utrafast shear wave imaging 3-plane acquisition provides several frames of breast lesion elasticity, that are reconstructed by means of a dedicated software thus permitting the direct volumetric elasticity measurements in kPa
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients having already undergone a breast MRI * Patients presenting with breast lesions measuring between20-50mm in ultrasound Exclusion Criteria: * Multifocal lesions * History of breast cancer * Breast implants * Inflammatory breast disease * Pregnancy
References
Publications (2)
- BACKGROUNDAthanasiou A, Tardivon A, Tanter M, Sigal-Zafrani B, Bercoff J, Deffieux T, Gennisson JL, Fink M, Neuenschwander S. Breast lesions: quantitative elastography with supersonic shear imaging--preliminary results. Radiology. 2010 Jul;256(1):297-303. doi: 10.1148/radiol.10090385. Epub 2010 May 26. PMID 20505064
- RESULTAthanasiou A, Latorre-Ossa H, Criton A, Tardivon A, Gennisson JL, Tanter M. Feasibility of Imaging and Treatment Monitoring of Breast Lesions with Three-Dimensional Shear Wave Elastography. Ultraschall Med. 2017 Jan;38(1):51-59. doi: 10.1055/s-0034-1398980. Epub 2015 Mar 5. PMID 25741668