Clinical trial · Interventional
Chinese Cancer Prevention Study(CHICAPS)
Chinese Cancer Prevention Study(CHICAPS) Mass Population Based Cervical Cancer Screening
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to develop and implement a community based preventive healthcare model using cervical cancer screening as the target medical intervention. The investigators will first conduct 2 pilot studies to refine their preventive healthcare model based on the principles of community based participatory research (1000 participants). The investigators will then apply the model to screen 9000 women for cervical cancer over a period of 7-9 days. This 10,000 patient trial will explore the ability of a community to conduct their own screening program to identify who needs medical intervention based on self-collection and centralized high-throughput low cost human papillomavirus (HPV) testing.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
| Cervical Dysplasia | Cervical Intraepithelial Neoplasia | ALIAS | 0.90 |
| Cervical Intraepithelial Neoplasia | Cervical Intraepithelial Neoplasia | ONTOLOGY_EXACT | 0.98 |
| Cervical Neoplasm | Cervical Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Human Papillomavirus | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Colposcopy | Procedure | — | UNRESOLVED |
| cryotherapy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Cryotherapy after VIA triage
- description
- Women who test HPV positive will be randomized to the experimental arm or the standard of care arm. In the Experimental arm VIA will be done to determine acceptability for cryotherapy \[R/O high-grade CIN too large for cryotherapy (usually 3-4 quadrant disease) or cancer\]. All acceptable patients will have an ECC done and then immediate cryotherapy.
- interventionNames
- Procedure: cryotherapy
- type
- ACTIVE_COMPARATOR
- label
- Colposcopy and biopsy
- description
- Standard of care. Women testing positive for HPV will be randomized to the experimental arm (immediate cryotherapy) or the Standard of care arm, for colposcopy, biopsy, and leep based on the pathology results.
- interventionNames
- Procedure: Colposcopy
Primary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 35 Years
- Maximum age
- 59 Years
Show eligibility criteria text
Inclusion Criteria: Inclusion Criteria 1. Non pregnant women 35-59 years of age. 2. No hysterectomy 3. No prior pelvic radiation. 4. Willing to sign consent form Exclusion Criteria: 1. Males 2. Women younger than 35 years old and older than 59 years old. 3. Pregnant women. 4. Patients with known history of hysterectomy or radiation for a pelvic cancer. 5. Refusal to participate
References
Publications (1)
- DERIVEDBelinson JL, Wang G, Qu X, Du H, Shen J, Xu J, Zhong L, Yi J, Yi X, Wu R. The development and evaluation of a community based model for cervical cancer screening based on self-sampling. Gynecol Oncol. 2014 Mar;132(3):636-42. doi: 10.1016/j.ygyno.2014.01.006. Epub 2014 Jan 14. PMID 24440471