Clinical trial · Observational
Long Term Diabetes Improvement After Cancer Gastrectomy and Colectomy
NCT01518023CI-TRIAL-00006128completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
There is evidence that gastrointestinal operations for non weight-losing purposes are beneficial for diabetes mellitus. Aiming to analyze such hypothesis, patients submitted to gastric bypass for morbid obesity, gastrectomy for gastric cancer and colectomy for colo-rectal cancer will be compared. The end point will be changes in fasting blood glucose and hemoglobin A1c concentration.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Diabetes Mellitus | — | UNRESOLVED | — |
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Morbid Obesity | — | UNRESOLVED | — |
| Prediabetes | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Interview, questionnaire, updated biochemical tests | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Cancer gastrectomy
- description
- Patients previously submitted to partial/total gastrectomy for gastric cancer
- interventionNames
- Other: Interview, questionnaire, updated biochemical tests
- label
- Colorectal cancer operation
- description
- Patients previously submitted to right colectomy or rectosignoidectomy for cancer
- interventionNames
- Other: Interview, questionnaire, updated biochemical tests
- label
- Bariatric patients
- description
- Morbidly obese participants who underwent antiobesity Roux-en-Y gastric bypass
- interventionNames
- Other: Interview, questionnaire, updated biochemical tests
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Follow-up period \> 3 years, * weight stable in the last year Exclusion Criteria: * Reoperation or take-down of original operation, * consumptive diseases, * protein-calorie malnutrition, * organ failures, * pancreatic surgery, * cell or organ transplantation, * type 1 diabetes, * cognitive impairment or Alzheimer disease, * refusal to participate in the protocol
References
Publications (3)
- BACKGROUNDFaintuch J, Yamaguchi CM, Dias MC, Santo MA, Faintuch JJ, Cecconello I. Biochemical correlates of bariatric-responsive diabetes. Diabetes Technol Ther. 2010 Sep;12(9):707-15. doi: 10.1089/dia.2010.0018. PMID 20707737
- BACKGROUNDKim JW, Cheong JH, Hyung WJ, Choi SH, Noh SH. Outcome after gastrectomy in gastric cancer patients with type 2 diabetes. World J Gastroenterol. 2012 Jan 7;18(1):49-54. doi: 10.3748/wjg.v18.i1.49. PMID 22228970
- DERIVEDHayashi SY, Faintuch J, Yagi OK, Yamaguchi CM, Faintuch JJ, Cecconello I. Does Roux-en-Y gastrectomy for gastric cancer influence glucose homeostasis in lean patients? Surg Endosc. 2013 Aug;27(8):2829-35. doi: 10.1007/s00464-013-2829-3. Epub 2013 Feb 23. PMID 23436087