Clinical trial · Observational
The Memorial Sloan-Kettering Cancer Center (MSKCC
Prospective Evaluation of the Reliability of the Combined Use of Two Models to Predict Non-sentinel Lymph Node Status in Breast Cancer Patients With Metastatic Sentinel Lymph Nodes: the MSKCC Nomogram and the Tenon Score.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to prospectively evaluate the combined use of the MSKCC nomogram (Memorial Sloan-Kettering Cancer Center) and Tenon score to select, in patients with metastatic sentinel lymph node (SN), those at low risk of metastatic non-SN in whom additional axillary lymph node dissection (ALND) could be avoided.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| no intervention : measure of score | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- patients candidates for the SN procedure
- description
- The study will focus on patients candidates for the SN procedure as recommended by Saint-Paul de VENCE initially in 2005 but modified in 2009.
- interventionNames
- Other: no intervention : measure of score
Primary outcomes (1)
- measure
- False negative rate in patients with both a ≤ 10% probability of metastatic non-SN with the MSKCC nomogram and a Tenon score ≤ 3.5 (i.e. low risk): proportion of patients with metastatic non-SN at additional ALND.
- timeFrame
- after the surgery
Secondary outcomes (2)
- measure
- To determine the impact on the reliability of the combined predictor of frozen section examination in light of his achievement or not, and its sensitivity.
- timeFrame
- after the surgery
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged over 18 years old with invasive breast cancer with an indication of SN procedure as recommended by Saint-Paul de VENCE in 2005 amended in 2009 * T1-2 breast cancer * Patients having social security coverage. Exclusion Criteria: * Patient under the age of 18. * Patient who had neoadjuvant chemotherapy. * Patient who had had radiotherapy to the ipsilateral axilla or breast. * Pregnant patient. * Patients who do not speak French. * Patients refusing to participate in the study. * Simultaneous participation in another research period of exclusion
References
Publications (0)
Data not yet available