Clinical trial · Observational

Biomarkers in Samples From Patients With B-Cell Acute Lymphoblastic Leukemia

Micro RNA Expression Analysis in B-Lineage Adult Acute Lymphoblastic Leukemia From ALL Trial, E2993, Including Patients With Various Cytogenetic and Molecular Abnormalities

NCT01505699CI-TRIAL-00027637completedClinicalTrials.gov clinicaltrialsPublishedExplore in graph →

Summary

Brief summary (as posted)

RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. PURPOSE: This research study is studying biomarkers in samples from patients with acute lymphoblastic leukemia enrolled on ECOG-2993 clinical trial.

Conditions

Conditions (1)

Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.

Condition (as posted)	Mapped entity	Match	Confidence
Leukemia	Leukemia	ONTOLOGY_EXACT	0.90

Interventions

Interventions (4)

Intervention	Type	Mapped drug	Match
cytogenetic analysis	Genetic	—	UNRESOLVED
laboratory biomarker analysis	Other	—	UNRESOLVED
microarray analysis	Genetic	—	UNRESOLVED
RNA analysis	Genetic	—	UNRESOLVED

Design

Arms and outcomes

Arms (0)

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Primary outcomes (3)

measure
Comprehensive view of microRNA expression by cytogenetic subgroup
timeFrame
1 year
measure
MicroRNA expression in relation to clinical outcome
timeFrame
1 year
measure
Differential microRNA expression between normal B-cells and progenitors compared to B-ALL
timeFrame
1 year

Eligibility

Eligibility (as posted)

Sex: All
Minimum age: 15 Years
Maximum age: 65 Years

Show eligibility criteria text

DISEASE CHARACTERISTICS:

* Samples from patients enrolled on ECOG-2993
* Samples from patients with recurrent cytogenetic abnormalities other than BCR-ABL, including MLL/AF4, E2A/PBX1, and TEL/AML1

PATIENT CHARACTERISTICS:

* Not specified

PRIOR CONCURRENT THERAPY:

* Not specified

References

Publications (0)

Data not yet available

No reference posted for this study.