Clinical trial · Observational
Genome-wide Association Study
Genome-wide Association Study to Predict Treatment Response for Chemotherapy in Esophageal Squamous Cell Carcinoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Registration poor
Summary
Brief summary (as posted)
To explore biomarkers predictive of clinical response to Taxane/5-FU/platinum based chemotherapy in esophageal squamous cell carcinoma. To identify negative predictive markers to 5-FU/platinum/Taxane. To elucidate signal transduction pathway attributable to 5-FU/platinum/Taxane resistance. To analyze correlation between the quantity of circulating tumor cells and circulating endothelial cell precursors and treatment response to Taxane/5-FU/platinum based chemotherapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Patients treated with Taxane/5-FU/platinum based chemo.
Primary outcomes (1)
- measure
- Biomarkers predictive
- timeFrame
- 24months
- description
- Biomarkers predictive of clinical response to Taxane or 5-fluorouracil or platinum based chemotherapy.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Histological confirmed esophageal squamous cell carcinoma * Patients treated with Taxane or 5-FU or platinum based chemotherapy. * provision of a signed written informed consent. Exclusion Criteria: * patients not signed written informed consent. * patient unacceptable for study in the judgement of the investigator.
References
Publications (0)
Data not yet available