Clinical trial · Observational
Autologous CIK Cells Infusion for the Treatment of Lung Cancer: a Randomized Controlled Study
A Randomized Controlled Trail on the Efficacy and Safety of Autologous Cytokine-induced Killer (CIK) Cells Infusion Treatment in Advanced Primary Lung Cancer
NCT01498055CI-TRIAL-00006561CIKunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To study the efficacy and safety of autologous CIK cells infusion for the treatment of lung cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- CIK therapy group
- label
- control group
Primary outcomes (1)
- measure
- Disease Control Rates (DCR)
- timeFrame
- From 12-2011 to 12-2013
- description
- Lung lesions of disease control rates DCR (CR + PR + SD), according to solid tumor response evaluation standard (response evaluation criteria in solid tumors, RECIST) standard
Secondary outcomes (1)
- measure
- Overall Survival(OS)
- timeFrame
- 2 years
- description
- Disease progression-free surial (Progression-Free Srvival, PFS) with observations
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * 18\~70 year old, KPS score \>50 points, estimate survival \> 3 months; * Primary lung cancer patients after chemotherapy or radiation therapy; * Primary lung cancer patients after targeted therapy; * Primary lung cancer patients with lung function can not accept operation or unwilling to operation; * Primary lung cancer recurrence or surgery can't complete resection; * Primary lung cancer patients after intervention therapy(I125 implanted, freezing, rf, etc.); * No serious mental illness and no serious heart, liver, kidney diseases, unincorporated other potentially lethal diseases; * Patients Voluntary attempt, and informed consent. Exclusion Criteria: * History of cardiovascular disease: congestive heart failure \> New York heart association (NYHA) level II, unstable angina patients (resting when the angina symptoms) or new happen angina pectoris (recent 3 months) or recent 6 months of myocardial infarction; * Cachexia; or other deadly diseases; * Liver function laboratory ALT, AST more than normal limits on 2.0 times ; Or kidney TBIL, BUN more than normal limits on 1.0 times , or Cr more than normal upper limit; * Active infection; * Pregnant or lactating women * At present Is receiving other cancer treatment (such as chemotherapy, radiation therapy, chemotherapy, immunosuppressants and thrombosis, targeted agents); * Now or recently will join another experimental clinical study ; * Other situations that the researchers considered unsuitable for this study (such as mental illness, drug abuse, HIV infections, etc.), or influence on the results of clinical trials for analysis.
References
Publications (0)
Data not yet available
No reference posted for this study.