Clinical trial · Observational
Biomarkers in Tumor Tissue Samples From Younger Patients With Rhabdomyosarcoma
Observational - CRKL Expression at the Protein Level in Rhabdomyosarcoma Tumors by Tissue Microarray (TMA)
NCT01496573CI-TRIAL-00022311completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research trial studies biomarkers in tumor tissue samples from younger patients with rhabdomyosarcoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Alveolar Childhood Rhabdomyosarcoma | Childhood Alveolar Rhabdomyosarcoma | ALIAS | 0.90 |
| Childhood Rhabdomyosarcoma | Childhood Rhabdomyosarcoma | ONTOLOGY_EXACT | 0.98 |
| Embryonal Childhood Rhabdomyosarcoma | Childhood Embryonal Rhabdomyosarcoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laboratory biomarker analysis | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Basic science (biomarker analysis)
- description
- Archived tumor tissue samples are analyzed for CRKL expression.
- interventionNames
- Other: laboratory biomarker analysis
Primary outcomes (1)
- measure
- CRKL expression at the protein level
- timeFrame
- 1 month
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Alveolar rhabdomyosarcoma and embryonal rhabdomyosarcoma specimens from the Children Oncology Group (COG) tumor microarrays (TMAs)
References
Publications (0)
Data not yet available
No reference posted for this study.