Clinical trial · Interventional
Effect of Carum Carvi on Thyroid Hormones and TSH Level
Evaluation of the Effect of Carum Carvi on Levels of Plasma Thyroid Hormones and TSH Level in Patients on Thyroid Hormone Therapy and Normal Controls.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Carum Carvi has been frequently used in traditional medicine for a variety of disease ranging from dyspepsia to Alzheimer's disease.We observed high TSH levels in few patients with thyroid cancer who receiving Carum Carvi despite being on suppressive dose of levothyroxin. TSH level returned to normal after discontinuation of the Carum carvi. This observation led to a pilot study for evaluation of the effect of carum carvi on thyroid function.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Cancer Patients | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Carum Cravi | Drug | — | UNRESOLVED |
| Placebo | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- ACTIVE_COMPARATOR
- label
- Group3
- description
- Normal controls
- interventionNames
- Drug: Carum Cravi
- type
- PLACEBO_COMPARATOR
- label
- Group4
- description
- Normal controls
- interventionNames
- Drug: Placebo
- type
- ACTIVE_COMPARATOR
- label
- Group 1
- description
- Hypothyroid patients taking levothyroxin.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18-65 * Hypothyroid patients under treatment with levothyroxin * Normal euthyroid patients with no goiter Exclusion Criteria: * Pregnancy or lactation * Severe lung or gasterointestinal disease * Heart failure or renal failure
References
Publications (0)
Data not yet available