Clinical trial · Interventional
Surgical Resection Lowers Oxidative Stress Markers in Patients With Colorectal Cancer
NCT01470586CI-TRIAL-00005762completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Study of Oxidative stress Markers (F2 Isoprostanes for lipid peroxidation, Carbonyl groups for protein peroxidation, 3 Nitrotyrosine for damage by nitrogens, and 8-Hydroxyguanosine for RNA peroxidation)in patients with colorectal cancer undergo surgical treatment (preoperatively during the intervention and postoperatively) and controls.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Rectal Resection | — | UNRESOLVED | — |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Oxidative Stress | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Surgery for colorectal cancer | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Surgery for colorectal cancer
- description
- Colorectal cancer patients
- interventionNames
- Procedure: Surgery for colorectal cancer
- type
- NO_INTERVENTION
- label
- Controls
- description
- Controls
Primary outcomes (1)
- measure
- Comparison of Oxidative stress markers in patients with colorectal cancer and controls
- timeFrame
- up to 2 years
- description
- Oxidative stress markers variation (8-PGF2α, Protein Carboyls, 3-Nitrotyrosine, 8-OHG) during and after surgery for colorectal cancer, and compare with controls
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 25 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with colorectal cancer * Controls Exclusion Criteria: * ASA\>3 * Metastatic Disease * Acute bowel obstruction * Acute bowel perforation * BMI\<30 * Chronic Systemic or Autoimmune Diseases * Smokers * Alcohol consumers
References
Publications (0)
Data not yet available
No reference posted for this study.