Clinical trial · Interventional
Trial of Ablation of Small Hepatocellular Carcinomas in Patients of Cirrhosis
NCT01438437CI-TRIAL-00007421unknownPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to assess the efficacy of Radiofrequency ablation (RFA) and percutaneous acetic acid ablation (PAI) in the management of small hepatocellular carcinoma (HCC) in patients of cirrhosis of liver.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PAI | Procedure | — | UNRESOLVED |
| RFA | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Percutaneous acetic acid
- interventionNames
- Procedure: PAI
- type
- ACTIVE_COMPARATOR
- label
- Radiofrequency ablation
- interventionNames
- Procedure: RFA
Primary outcomes (1)
- measure
- Local tumor response
- timeFrame
- 2 years
Secondary outcomes (3)
- measure
- Survival rate
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 12 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Child's A or B cirrhosis with liver mass. * Number of liver masses not more than 5 and the size of each \<5cm in diameter. * No extrahepatic disease. * Absence of malignant portal vein thrombosis. * Platelet count more than 70,000/mm3 * Prothrombin time more than 50%. * Written consent of patient. Exclusion Criteria: * Childs'C cirrhosis with liver mass. * Liver mass \>5cm in diameter. * Number of liver masses more than 3 * Peripherally located masses with no hepatic parenchyma around * Liver mass not discernable on ultrasound. * Extra hepatic disease like RP adenopathy, distant metastasis. * Coagulation disorders. * Unwilling patient
References
Publications (0)
Data not yet available
No reference posted for this study.