Clinical trial · Observational
Pilot Study of Model Based Iterative Reconstruction Using 64-Slice
Pilot Study of Model Based Iterative Reconstruction Using 64-Slice Multidetector-Row CT Datasets Obtained From the Central Nervous System, Thorax, and Abdomen
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Feasibility study, sufficient amount of data collected.
Summary
Brief summary (as posted)
This study is being performed to confirm that the new technique, Model-Based Iterative Reconstruction (MBIR) with reduced radiation dose can deliver equivalent image quality for CT scans compared to current techniques (Filtered Back Projection with Adaptive Statistical Iterative Reconstruction (FBP with ASiR) and also to demonstrate that MBIR can improve general image quality characteristics at equivalent radiation dose levels.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Flank Pain | — | UNRESOLVED | — |
| Focal Hepatic Necrosis | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Posterior Fossa Hemorrhage | — | UNRESOLVED | — |
| Urolithiasis | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (4)
- label
- CNS
- description
- CNS: Known or suspected pathology in the posterior fossa
- label
- Thorax
- description
- Thorax: Patients referred for staging of a known or suspected lung cancer
- label
- Abdomen 1
- description
- Abdomen: Patients with acute flank pain and suspected urolithiasis
- label
- Abdomen 2
- description
- Abdomen: Patients with a known or suspected focal liver lesion
Primary outcomes (1)
- measure
- Evidence for reduced x-ray radiation exposure for applicable patient indications
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 30 Years
Show eligibility criteria text
Inclusion Criteria: * Men or Women 30 years of age or older voluntarily willing to sign an informed consent. * Patients indicated for one of the following: CNS: Known or suspected pathology in the posterior fossa Thorax: Patients referred for staging of a known or suspected lung cancer Abdomen: Patients with acute flank pain and suspected urolithiasis or Abdomen: Patients with a known or suspected focal liver lesion Exclusion Criteria: * Subjects less than 30 years of age * Pregnant women as confirmed by urine test or current accepted institution standard * If IV contrast is required: * Severe or uncontrolled allergy to iodinated contrast media * Serum creatinine \> 1.7 mg/dl or estimated glomerular filtration rate \[eGFR\] of \<60 mg/min as recorded in medical file or by current accepted institution standard * Unable or unwilling to provide written informed consent by self or legal guardian at the time of study enrollment * Unstable physical condition as identified by physician
References
Publications (0)
Data not yet available