Clinical trial · Interventional
Inflammatory Response After Colorectal Cancer Surgery
Inflammatory Response Following Colorectal Cancer Surgery Depends on the Type of Anesthesia and Surgery
NCT01427647CI-TRIAL-00023206CRCcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Laparoscopic technique and epidural anesthesia have been proposed to improve postoperative outcome following colorectal cancer surgery. The investigators hypothesize that the inflammatory response is attenuated by laparoscopic surgery and epidural anesthesia compared to traditional open surgery under general anesthesia.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic technique and thoracic epidural anesthesia | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Control group
- description
- Control group: open surgery under general anesthesia
- interventionNames
- Procedure: Laparoscopic technique and thoracic epidural anesthesia
- type
- ACTIVE_COMPARATOR
- label
- Epidural group
- description
- Epidural group: Open surgery under thoracic epidural anesthesia
- interventionNames
- Procedure: Laparoscopic technique and thoracic epidural anesthesia
- type
- ACTIVE_COMPARATOR
- label
- Laparoscopic group
- description
- Laparoscopic group: Laparoscopic surgery under general anesthesia
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients scheduled for colorectal cancer surgery Exclusion Criteria: * Emergent surgery * Intestinal obstruction * Contraindication for epidural catheter placement * Concomitant autoimmune disease * Concomitant infectious disease * Recent corticosteroids or anti-inflammatory medications
References
Publications (0)
Data not yet available
No reference posted for this study.