Clinical trial · Interventional
Non-Invasive Imaging for Cording in Breast Cancer Patients
Evaluation of Non Invasive Imaging for Assessing the Pathophysiology of Cording in Patients Treated for Breast Cancer
NCT01427166CI-TRIAL-00021379completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To date, the scientific literature has yet to provide sufficient evidence regarding the pathophysiology of cording. The objective of this protocol is to evaluate the utility of non invasive vascular imaging for assessing the pathophysiology of cording in a small study cohort of patients who were treated for breast cancer. The hypothesis is that cording may have a vascular etiology
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Non invasive venous ultrasound | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Ultrasound imaging
- description
- Cords that are present in the participant's axilla and/or arm will be imaged with an ultrasound
- interventionNames
- Other: Non invasive venous ultrasound
Primary outcomes (1)
- measure
- The pathophysiology of cording following treatment for breast cancer
- timeFrame
- 7 days
- description
- The cohort of 15 subject's images will be reviewed by the PI and a designated physician from the department of vascular medicine to determine if there is a vascular origin in the cords. Each image will be accessed for the following findings or involvement: Venous, lymphatic, fluid pockets, and striations on the cord.
Secondary outcomes (1)
- measure
- Cording and the onset of breast cancer related lymphedema
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Participants must be enrolled in Partners protocol # 2008P000540 "Prospective Analysis of Symptoms, Functionality and Quality of Life Questionnaires to Evaluate Lymphedema in Patients Following Treatment for Breast Cancer" * Confirmed case of cording by a medical provider (Physician, Nurse Practitioner, Physician Assistant) * Participants must be at least 18 years of age * Life expectancy of greater than 1 year. * Ability to understand and the willingness to sign a written informed consent document. * Willingness to comply with required follow up Perometer measurements and clinical visits. Exclusion Criteria: * Participants who are not enrolled or have been removed from Partners Protocol # 2008P000540 will be excluded from this trial. * Participants with known brain metastases should be excluded from this clinical trial because of their poor prognosis and because they often develop progressive neurologic dysfunction that would confound the evaluation of neurologic and other adverse events. * History of prior surgery or radiation to the head, neck, upper limb, or trunk. * Patients with a history of a different malignancy are ineligible except for the following circumstances. Individuals with a history of other malignancies are eligible if they have been disease-free for at least 5 years and are deemed by the investigator to be at low risk for recurrence of that malignancy. Individuals with the following cancers are eligible if diagnosed and treated within the past 5 years: cervical cancer in situ, and basal cell or squamous cell carcinoma of the skin.
References
Publications (0)
Data not yet available
No reference posted for this study.