Clinical trial · Observational
Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome
The Brain Vascular Malformations Clinical Research Network: Predictors of Clinical Course, Project 2: Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome
NCT01425944CI-TRIAL-00104379active not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study has three aims that hope to expand the knowledge on the cause of Sturge-Weber Syndrome (SWS) and improve clinical care of Sturge-Weber Syndrome patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Sturge-Weber Syndrome | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- Aim 1
- timeFrame
- All 5 years
- description
- Descriptive statistics for the national database, correlation between neurologic score and urine angiogenesis factor, and correlation between PWS (port-wine stain) attributes, urine vascular factors, and neuroscore
- measure
- Aim 2
- timeFrame
- All 5 years
- description
- Correlation between neuroscore and degree of collateral venous vessel opening
- measure
- Aim 3
- timeFrame
- All 5 years
- description
- Correlation between GNAQ mutation status and hyperphosphorylation in downstream proteins
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 1 Month
Show eligibility criteria text
Inclusion Criteria: For Aim 1: For main sample: * Sturge-Weber syndrome * Diagnosed brain Involvement For Control: * Family member of participating SWS patient For OCT: * Sturge-Weber syndrome eye involvement For Aim 2: * Sturge-Weber syndrome * Diagnosed Brain Involvement For Aim 3: * Sturge-Weber syndrome * Diagnosed brain Involvement * Port-Wine Stain in V1 and/or V2 areas of face. Exclusion Criteria: * Not Diagnosed with Sturge-Weber syndrome with brain Involvement (or eye involvement for OCT) For Aim 1: * Family member must not have certain medical conditions. A list will be provided before consent is given. For Aim 3: * Not Diagnosed with Sturge-Weber syndrome with brain Involvement * No Port-Wine Stain
References
Publications (0)
Data not yet available
No reference posted for this study.