Clinical trial · Interventional
Using Rapid Cine-MRI for Monitoring Moving and Deforming Tumors
Investigating the Feasibility of Using Rapid Cine-MRI for Monitoring Moving and Deforming Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): PI left the institution
Summary
Brief summary (as posted)
In this study, the researchers investigate the feasibility of using rapid cine MR imaging to provide both offline and online soft-tissue-based image guidance. Such images will provide a significantly more complete picture of the spatial and temporal changes in thoracic anatomy. This more complete information will lay the groundwork for better radiotherapy planning and dose delivery in the presence of respiratory motion.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| cine MRI | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Cine-MRI
- description
- Rapid Cine-MRI
- interventionNames
- Other: cine MRI
Primary outcomes (1)
- measure
- To measure time series of MRI imaging by the b-SSFP sequence.
- timeFrame
- 6 weeks
- description
- To use fast acquisition sequences to obtain 2D and 3D cine MR images of moving and deforming lung tumors. The signal to noise ration (SNR) and spatiotemporal resolution of imaging sequences will be optimized into a format potentially useful for radiotherapy guidance.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * AJCC Stage I, II, III or IV non-small-cell lung cancer to be treated using radiotherapy will be eligible for this study. * Any types and amounts of prior therapy will be allowed for this study. * Subjects must be greater than or equal to 18 years of age. There are no gender or ethnic restrictions. * Ability to understand and the willingness to sign a written informed consent document. * Able to tolerate supine position * ECOG performance status of 3 or less Exclusion Criteria: * MRI-incompatible metallic implants, embedded metallic objects, implanted biomedical devices e.g., cardiac pacemakers * Women who are pregnant or trying to get pregnant * Pain in supine position
References
Publications (0)
Data not yet available