Clinical trial · Observational
Study of Proteins in Tumor Samples From Patients With Non-Small Cell Lung Cancer
Evaluation of a Novel Molecular NSCLC Classification System
NCT01415739CI-TRIAL-00036730withdrawnClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Trial closure due to NCI NCTN transition
Summary
Brief summary (as posted)
This research studies protein in tumor samples from patients with non-small cell lung cancer. Finding specific proteins in tumor tissue samples from patients with cancer may help doctors tell what type of lung cancer a patient has and plan better treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laboratory biomarker analysis | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Novel Molecular NSCLC Classification (H & E staining, IHC)
- description
- Previously collected tissue samples are analyzed via H\&E staining and IHC.
- interventionNames
- Other: laboratory biomarker analysis
Primary outcomes (1)
- measure
- Validation of a novel 4-protein signature's ability to subtype NSCLC
- timeFrame
- 1 month
Secondary outcomes (1)
- measure
- NSCLC misclassification rate
- timeFrame
- 1 month
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients must have been registered on CALGB-9761 * Stage I disease * Treatment-naive patients * A representative paraffin block of the primary tumor must be available from patients on CALGB-9761 and submitted to the CALGB Pathology Coordinating Office * A separate consent form is not required for this study, as permission for research to be performed on the tissue blocks is included in the consent form for CALGB 9761 * Institutional review board (IRB) review and approval at the institution where the laboratory work will be performed is required
References
Publications (0)
Data not yet available
No reference posted for this study.