Clinical trial · Observational
Study of Tissue Samples From Patients With Non-Small Cell Lung Cancer
Molecular Characterization of Lung Cancer: A Collaboration With the Cancer Genome Atlas Project (TGCA)
NCT01414595CI-TRIAL-00028284completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research trial studies tissue samples from patients with non-small cell lung cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (7)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| DNA analysis | Genetic | — | UNRESOLVED |
| DNA methylation analysis | Genetic | — | UNRESOLVED |
| gene expression analysis | Genetic | — | UNRESOLVED |
| laboratory biomarker analysis | Other | — | UNRESOLVED |
| medical chart review | Other | — | UNRESOLVED |
| polymorphism analysis | Genetic | — | UNRESOLVED |
| RNA analysis | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Group 1
- description
- CALGB 140202 outlines the standard procedures for sample procurement. Samples to be used for this project have already been obtained and are currently banked at the CALGB Pathology Coordinating Office (PCO) and the Lung Cancer Tissue Bank at Brigham and Women's Hospital.
- interventionNames
- Genetic: DNA analysis
- Genetic: DNA methylation analysis
- Genetic: RNA analysis
- Genetic: gene expression analysis
- Genetic: polymorphism analysis
- Other: laboratory biomarker analysis
- Other: medical chart review
Primary outcomes (3)
- measure
- Identification and characterization of SNVs in primary adenocarcinoma of the lung or squamous cell carcinoma of the lung
- timeFrame
- up to 5 years
- measure
- Identification and characterization of structural variations in the genomes of NSCLC
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
* Patient must have been registered to CALGB 140202. * Tumor histology should be either primary adenocarcinoma or squamous cell carcinoma of the lung. * Patients are eligible for this study if their samples from CALGB 140202 are available. * All living patients must sign the CALGB 151107 consent form to be eligible for this trial.
References
Publications (0)
Data not yet available
No reference posted for this study.