Clinical trial · Interventional
A Novel Magnetic Needle Using Iron Oxide Nanoparticles for the Detection of Leukemia
NCT01411904CI-TRIAL-00020165withdrawnN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): The NPs that we have been buying from a vendor show lot to lot variation. We are making our own NPs, need to characterize them before we enroll new patients.
Summary
Brief summary (as posted)
The purpose of this study is to determine if the magnetic needle, in combination with magnetic nanoparticles can accurately identify minimal residual disease in leukemia patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Leukemia | Leukemia | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MagProbe (TM) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- MagProbe (TM)
- description
- Patients whose bone marrow aspirates are exposed to the MagProbe and CD34 nanoparticles. Leukemia patients * MagProbe (TM) * Diagnosed or suspected leukemia Non-leukemia patients * MagProbe (TM) * Requiring bone marrow biopsy
- interventionNames
- Device: MagProbe (TM)
Primary outcomes (1)
- measure
- Lymphoblast percent
- timeFrame
- 1 day
- description
- Lymphoblast percent calculated before exposure to needle and of the needle enhanced sample
Secondary outcomes (1)
- measure
- SQUID magnetometry
- timeFrame
- 1 day
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Group: Leukemia Patients Inclusion Criteria: * Suspected diagnosis of Leukemia * Requiring bone marrow biopsy for standard care Exclusion Criteria: * unable to consent for entrance into the study Group: Non-leukemia Patients Inclusion Criteria: * Requiring bone marrow biopsy for standard care Exclusion Criteria: * unable to consent for entrance into the study * Leukemia diagnosis
References
Publications (0)
Data not yet available
No reference posted for this study.