Human Ovarian Autotransplantation

Chemotherapy can cause permanent damage to a woman's ovaries. Women who are cancer survivors may find that they are not able to produce female hormones, and they may not be able to have a child. Scientists are trying to find ways to help cancer survivors regain their hormonal function and possibly get pregnant, if they desire. Scientists have developed a method where ovarian tissue is removed and frozen before chemotherapy; then it is thawed and put back into the woman's body after she is cancer-free. Putting a woman's previously-frozen tissue back into her body is called ovarian autotransplantation. Ovarian autotransplantation is a very new technique, and there have only been a small number of women who have had this procedure. So far, only five babies in the world have been born using this technique. The purpose of this study is to learn more about ovarian autotransplantation. Scientists hope to find better ways to use this method to help a woman's ovaries start working again after chemotherapy. If the ovaries start working again, it might be possible to have a baby.

Sex

Female

Minimum age

18 Years

Maximum age

40 Years

Inclusion criteria:

* Adult women (age between 18 and 40) who stored the ovary before cancer therapy.
* Adult women who completed cancer therapy and are in remission.
* Adult women who desire to conceive and are ready to have a baby.

Exclusion criteria:

* Age under 18 or over 40 years old
* Women with a disease at high risk for ovarian metastasis (such as leukemia)
* Women with contraindication for surgery
* Women with contraindication for pregnancy
* Psychological instability to sustain pregnancy (diagnosed by a psychiatrist)
* Women who are HIV Positive