Clinical trial · Interventional
Impact of Computer-Aided Detection (CAD) as Second Reader in CT Colonography
Measure of Performances of CT Colonography With Computer-Aided Detection (CAD) as Second Reader in Detecting Colorectal Lesion
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: CT colonography accurately detects large polyps and masses. However, the test is less accurate in identifying lesions between 6 and 9 mm.Use of computer-aided detection (CAD) has shown promising results in providing uniform accuracy and improving CT colonography sensitivity. PURPOSE:This clinical trial compared the performance of CT colonography with unassisted and CAD-assisted reading in detecting patients with colorectal lesions.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Individuals With Suspected Colorectal Disease | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| colonoscopy | Procedure | — | UNRESOLVED |
| CT colonography | Procedure | — | UNRESOLVED |
| CT Colonography with computer assisted diagnosis (CAD),CADCOLON -im3D SpA., Torino Italy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Sensitivity of CT colonography with unassisted and CAD-assisted reading in detecting individuals with lesions 6 to 9 mm
- measure
- Specificity of CT colonography with unassisted and CAD-assisted reading in detecting individuals with no clinical relevant lesions
Secondary outcomes (2)
- measure
- Sensitivity of CT colonography with unassisted and CAD-assisted reading in detecting individuals with lesions 10 mm or larger
- measure
- Sensitivity of CT colonography with unassisted and CAD-assisted reading in detecting lesions 6 mm or larger
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: \- clinical indication to undergo colonoscopy either for symptoms, or participating a surveillance program or a CRC screening Exclusion Criteria: * clinical diagnosis of familial adenomatous polyposis or hereditary nonpolyposis CRC syndrome * inflammatory bowel disease * celiac disease * evidence of increased risk of harm from colonoscopy * psychological or physical conditions that contraindicated colonoscopy or CT Colonography
References
Publications (1)
- DERIVEDRegge D, Della Monica P, Galatola G, Laudi C, Zambon A, Correale L, Asnaghi R, Barbaro B, Borghi C, Campanella D, Cassinis MC, Ferrari R, Ferraris A, Hassan C, Golfieri R, Iafrate F, Iussich G, Laghi A, Massara R, Neri E, Sali L, Venturini S, Gandini G. Efficacy of computer-aided detection as a second reader for 6-9-mm lesions at CT colonography: multicenter prospective trial. Radiology. 2013 Jan;266(1):168-76. doi: 10.1148/radiol.12120376. Epub 2012 Nov 14. PMID 23151831