Clinical trial · Observational
Polymorphisms in the Vitamin D System and Health
NCT01395303CI-TRIAL-00024780completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Polymorphisms in the vitamin D system appear to affect the serum 25(OH)D levels. If so one would expect these polymorphisms to be associated with vitamin D related conditions and diseases, which will be tested in the present study including DNA analyses in 9700 subjects
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Aortic Stenosis | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Death | — | UNRESOLVED | — |
| Diabetes | — | UNRESOLVED | — |
| Fracture | — | UNRESOLVED | — |
| Infarction | — | UNRESOLVED | — |
| Stroke | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (8)
- label
- myocardial infarction
- description
- subjects with myocardial infarction in the Tromsø study end point registry
- label
- type 2 diabetes
- description
- subjects with type 2 diabetes in the Tromsø study end point registry
- label
- stroke
- description
- subjects with stroke in the Tromsø study end point registry
- label
- fracture
- description
- subjects with fracture in the Tromsø study end point registry
- label
- cancer
- description
- subjects with cancer in the Tromsø study end point registry
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 30 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * participated in the fourth Tromsø study, later registered in our end point registry or selected as a control subject Exclusion Criteria: * lacking DNA sample
References
Publications (1)
- DERIVEDJorde R, Schirmer H, Wilsgaard T, Joakimsen RM, Mathiesen EB, Njolstad I, Lochen ML, Figenschau Y, Berg JP, Svartberg J, Grimnes G. Polymorphisms related to the serum 25-hydroxyvitamin D level and risk of myocardial infarction, diabetes, cancer and mortality. The Tromso Study. PLoS One. 2012;7(5):e37295. doi: 10.1371/journal.pone.0037295. Epub 2012 May 23. PMID 22649517