Clinical trial · Observational
The Jewels in Our Genes Study - an African American Family Study of Breast Cancer
Search for Novel Breast Cancer Susceptibility Genes in Pedigrees of African Ancestry
NCT01380925CI-TRIAL-00022102completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The research team is studying why some African American families have multiple cases of breast cancer. This study will help to better understand if there are undiscovered genes unique to African Americans that may predict early breast cancer risk. Breast cancer survivors AND their relatives who are also breast cancer survivors are being recruited to the study.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- breast cancer
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Black/African American * Ever diagnosed with breast cancer * Have at least one living blood relative ever diagnosed with breast cancer, who is also willing to participate * Live in the U.S. Exclusion Criteria: * Tested positive for BRCA mutations
References
Publications (1)
- RESULTOchs-Balcom HM, Sun X, Chen Y, Barnholtz-Sloan J, Erwin DO, Jandorf L, Sucheston-Campbell L, Elston RC. Putative linkage signals identified for breast cancer in African American families. Cancer Epidemiol Biomarkers Prev. 2015 Feb;24(2):442-7. doi: 10.1158/1055-9965.EPI-14-1131. Epub 2014 Dec 4. PMID 25477366