Clinical trial · Observational
Molecular Imaging of Epidermal Growth Factor Receptor in Colorectal Neoplasia Using Confocal Laser Endomicroscopy
In Vivo Molecular Imaging of Epidermal Growth Factor Receptor in Patients With Colorectal Neoplasia Using Confocal Laser Endomicroscopy
NCT01372189CI-TRIAL-00006169completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study aims to: 1. Achieve molecular imaging of EGFR in patients with colorectal neoplasia in vivo using confocal laser endomicroscopy. 2. Compare the results of in vivo EGFR-specific molecular imaging with CLE and ex vivo immunohistochemistry .
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Adenoma | Colorectal Adenoma | ONTOLOGY_EXACT | 0.98 |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- colorectal cancer
- description
- Patients with colorectal carcinoma during conventional endoscopic imaging.
- label
- colorectal adenoma
- description
- Patients with colorectal adenoma during conventional endoscopic imaging.
Primary outcomes (0)
[]Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria： ●Patients known to have large polypoid lesions in colon or rectum from previous examinations from outpatients and inpatients at Qilu Hospital were enrolled into the study Exclusion Criteria: * Patients who are allergic to fluorescein sodium * Patients with impaired cardiac, liver or renal function * Patients who are unwilling to sign or give the informed consent form * Patients with giant tumors or obvious GI tract bleeding which make it hard or impossible to observe the lesions * Patients with coagulopathy * Patients with pregnancy or breastfeeding
References
Publications (0)
Data not yet available
No reference posted for this study.