Clinical trial · Interventional
Clearance Of Mucus In Stents (COMIS)
NCT01370278CI-TRIAL-00069087completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical research study is to compare the effects of sodium bicarbonate to normal saline when used for clearing mucus blockage in patients with airway stents.
Conditions
Conditions (8)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Coronary Syndromes | — | UNRESOLVED | — |
| Cardiac Arrhythmia | — | UNRESOLVED | — |
| Lung Neoplasms | Lung Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Myocardial Infarction | — | UNRESOLVED | — |
| Pneumonia | — | UNRESOLVED | — |
| Respiratory Failure | — | UNRESOLVED | — |
| Thromboembolic Disease | — | UNRESOLVED | — |
| Unstable Angina | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Normal Saline | Other | — | UNRESOLVED |
| Sodium Bicarbonate | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Normal Saline
- description
- Normal saline sprayed into stent/airway tubes then suctioned out through bronchoscope.
- interventionNames
- Other: Normal Saline
- type
- ACTIVE_COMPARATOR
- label
- Sodium Bicarbonate
- description
- Sodium bicarbonate sprayed into stent/airway tubes then suctioned out through bronchoscope.
- interventionNames
- Other: Sodium Bicarbonate
Primary outcomes (1)
- measure
- Percentage of obstruction resolution as Good or Excellent
- timeFrame
- Baseline to 7 days
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Adult patients (\>/= 18 years) with airway stents undergoing bronchoscopy. 2. Patients previously enrolled, but excluded as no stent lumen obstruction from mucus retention identified at earlier enrollment (hence excluded at that enrollment) . Exclusion Criteria: 1. Patients with history of allergy or adverse reactions to sodium bicarbonate or normal saline. 2. Patients refusing to sign informed written consent for participation in research. 3. Patients with no stent lumen occlusion from mucus impaction as determined at the time of the initial visual bronchoscopic assessment. 4. Previously enrolled patients who completed this protocol.
References
Publications (0)
Data not yet available
No reference posted for this study.