Clinical trial · Interventional
Circumferential Submucosal Incision Endoscopic Mucosal Resection Versus Conventional Endoscopic Mucosal Resection of Colonic Polyps
Circumferential Submucosal Incision Endoscopic Mucosal Resection Versus Conventional Endoscopic Resection for the Removal of Large Laterally Spreading Tumours and Sessile Polyps of the Colon
NCT01369316CI-TRIAL-00087737CSIEMRwithdrawnN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): study abandoned
Summary
Brief summary (as posted)
That Circumferential Submucosal Incision Endoscopic Mucosal Resection (CSI-EMR) will be at least as safe but more effective than conventional EMR for injection assisted EMR of large laterally spreading tumour and sessile polyps of the colon.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colonic Polyps | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Circumferential Submucosal Incision Resection | Procedure | — | UNRESOLVED |
| Endoscopic Mucosal Resection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Circumferential Submucosal Incision Resection
- interventionNames
- Procedure: Circumferential Submucosal Incision Resection
- type
- ACTIVE_COMPARATOR
- label
- Endoscopic Mucosal Resection
- description
- Patients randomised into this arm will receive the conventional treatment Endoscopic Mucosal Resection in which the sessile lesion is injected and snared by piecemeal technique.
- interventionNames
- Procedure: Endoscopic Mucosal Resection
Primary outcomes (1)
- measure
- Efficacy of CSI EMR (Rates of en-bloc resection, recurrence rates)
- timeFrame
- 3 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 95 Years
Show eligibility criteria text
Inclusion Criteria: * Can give informed consent to trial participation * Age greater than 18 * Adenomas that have not have previously been attempted for resection (i.e. naïve lesions) * Adenoma size greater than 20 mm Exclusion Criteria: * Age less than 18 * Previous resection or attempted resection of target adenoma lesion * Pregnant patients
References
Publications (0)
Data not yet available
No reference posted for this study.